Merritt B. Andrus
Dr. Merritt B. Andrus leads the Andrus Laboratory Group, which focuses on methods for the synthesis of biologically active natural products that possess unique structures and have potential for combinatorial library construction and screening. The chemicals the Andrus Laboratory Group synthesizes have implications in the treatment of cancer and heart disease.
Steven L. Castle
The Castle Research Group focuses on the total synthesis of architecturally complex bioactive natural products and peptides. The structures of such compounds can serve as inspiration for the invention of new organic reactions and processes and the development of new therapeutic agents.
Daniel H. Ess
Dr. Ess's research group utilizes and develops quantum-chemistry methods to discover mechanisms, reactivity principles, and selectivity for experimentally important chemical reactions related to catalysis, energy, and organic synthesis. Dr. Ess and his students focus on transition-metal catalysis and organic catalysis.
David J. Michaelis
Dr. Michaelis manipulates the size, molecular structure, and shape of transition-metal nanoparticles through the synthesis of polymer support structures and other means. These altered nanoparticles have applications in optics, electronics, sensing, medicine, and catalysis.
Matt A. Peterson
Dr. Peterson focuses on the chemical synthesis and biological evaluation of antitumor and antiviral compounds. Through the modification of naturally occurring nucleosides, Dr. Peterson and his students synthesize compounds that can inhibit cancers and HIV.
Joshua L. Price
Dr. Price utilizes post-translational modifications in order to stabilize proteins, which helps protein drugs last longer in the blood stream. These drugs can be used to treat cancer, macular degeneration, autoimmune diseases, and other conditions.
Paul B. Savage
The Savage Research Lab focuses on membrane-active antibiotics and glycolipid immunology. Through the use of small-molecule mimics of antimicrobial peptides, Dr. Savage is researching the mechanism of antibacterial activity and optimizing medical device coatings to prevent bacterial colonization. Dr. Savage's lab also studies the structural requirements of glycolipids for stimulation of natural killer T cells.